Molecular mechanisms of HF
- Förderkennzeichen
81Z2710107
- Projektnummer
484
- Institution
- Universitätsklinikum Hamburg-Eppendorf
- Projektleiter
- Dirk Westermann
- Standort
- Hamburg/Kiel/Lübeck
- Kurzbeschreibung
-
Our goal is to describe molecular mechanisms involved in heart failure pathology. Therefore, our research is focused on the extracellular matrix remodelling and the regulation of cardiac …
Our goal is to describe molecular mechanisms involved in heart failure pathology. Therefore, our research is focused on the extracellular matrix remodelling and the regulation of cardiac inflammation in different types of heart failure. Different animal models were used to induce heart failure. Furthermore, we combine in vivo animal models with in vitro cell culture experiments as well as the analysis of human samples to describe molecular mechanisms involved in heart failure pathology. Special focus will be on cardiac remodeling and changes in the extracellular matrix.
- Projektart
- Standortprojekt
- Stichwörter
- Heart failure, extracellular matrix, inflammation
- Topic
- cardiac hypertrophy/remodeling
- Fördersumme
- € 292.596,06
- Beginn
- 29.10.2014
- Ende
- 31.12.2018