Clinical CHD - Clinical Platelet Therapy Research


Förderkennzeichen

81Z1600214

Projektnummer

434

Institution
Klinikum der Universität München
Projektleiter
Steffen Massberg
Standort
München
Kurzbeschreibung

Platelets are central mediators of arterial thrombosis and the main target of treatment as well as prophylaxis of coronary heart disease. However, despite improvements in antiplatelet … 

Platelets are central mediators of arterial thrombosis and the main target of treatment as well as prophylaxis of coronary heart disease. However, despite improvements in antiplatelet therapy thrombotic disorders a still a leading cause of mortality worldwide. Therefore, the central aim of this project is to pave the way for innovative therapeutic approaches targeting the prothrombotic functions of platelets. This is based on an improved understanding of the interactions of platelets with the coagulation as well as the immune system using state-of-the-art basic science approaches and reaching to clinical evaluation. The results of this project will provide valuable insight into the mechanisms of thrombotic disorders and will break new ground for the treatment of coronary heart disease.

Projektart
Standortprojekt
Stichwörter
platelet, thrombosis, immune cells, coagulation
Topic
platelet function/thrombosis mechanisms
Fördersumme
€ 1.567.485,72
Beginn
01.05.2013
Ende
31.12.2018