Clinician Scientist Programme: Assessment of cardiac wasting-induced cardiomyopathy with cardiac MRI in advanced cancer patients


Förderkennzeichen

81X3100218

Projektnummer

1617

Institution
Charité - Universitätsmedizin Berlin
Projektleiter
Sara Hadzibegovic
Standort
Berlin
Kurzbeschreibung

The aim of this translational study is to research the underlying pathophysiology of cardiac wasting-induced cardiomyopathy in advanced stage cancer patients. A comprehensive assessment … 

The aim of this translational study is to research the underlying pathophysiology of cardiac wasting-induced cardiomyopathy in advanced stage cancer patients. A comprehensive assessment including cardiac MRI, biobanking and cardiorespiratory reflex physiology will be performed in 96 advanced stage cancer patients (without severe CV disease or active infection) and compared to 24 healthy controls and 48 patients with heart failure (HF) (all similar age and a 50:50 male/female ratio). The status of all patients and controls will be reassessed after 4 and 8 months. This project will provide new insights for further translational research projects and clinical therapeutic developments in cardio-oncology.

Projektart
Exzellenzprogramm
Fördersumme
€ 149.995,02
Beginn
01.10.2022
Ende
30.09.2025