Targeted intervention strategies for inflammation-induced heart and skeletal muscle failure


Funding ID

81Z0400108

Project number

2059

Institution
Universitätsmedizin Greifswald
Project leader
Jens Fielitz
Site
Greifswald
Short description

Our overall aim is to investigate targeted intervention strategies to treat SICM and inflammation-induced muscle wasting. We want to decipher inflammation-induced changes in protein … 

Our overall aim is to investigate targeted intervention strategies to treat SICM and inflammation-induced muscle wasting. We want to decipher inflammation-induced changes in protein degradation pathways in SICM and inflammatory muscle failure in vivo and in vitro. Using a preclinical mouse model, we will test the translational potential of identified pathways in SICM and inflammatory muscle failure.

Project type
Partner Site Projects
Funding
€ 1.443.971,00
Begin
01.01.2026
End
31.12.2030