DZHK Paper of the month

The RNA editor ADAR2 promotes immune cell trafficking by enhancing endothelial responses to interleukin-6 during sterile inflammation. DZHK authors: Giorgia Ciliberti, Jedrzej Hoffmann, Andre Schneider, Stefan Guenther, Johannes Backs, Thomas Braun, Stefanie Dimmeler, Markus...

The Board of Directors has selected two publications as the Paper of the Month for April:

The DZHK research platform: maximisation of scientific value by enabling access to health data and biological samples collected in cardiovascular clinical studies. DZHK authors: Julia Hoffmann, Sabine Hanss, Monika Kraus, Jens Schaller, Christian Schäfer, Dana Stahl, et al. Clin...

Loss of soluble guanylyl cyclase in platelets contributes to atherosclerotic plaque formation and vascular inflammation. DZHK authors: Carina Mauersberger, Hendrik Sager, Tan An Dang, Laura Lambrecht, Heribert Schunkert, Thorsten Kessler. Nat Cardiovasc Res (2022). doi:...

Targeting myeloid cell coagulation signaling blocks MAP kinase/TGF-beta1 driven fibrotic remodeling in ischemic heart failure. DZHK authors: V. Garlapati, M. Molitor, S. Finger, J. Wild, S. Karbach, T. Münzel, A. Daiber, M. Brandt, T. Gori, S. Tenzer, W. Ruf, P. Wenzel. J Clin...

Lamin A/C-dependent chromatin architecture safeguards naive pluripotency to prevent aberrant cardiovascular cell fate and function. DZHK authors: Yinuo Wang, Julio Cordero, Haojie Shi, Felix Trogisch, Mona Malek Mohammadi, Johannes Backs, Thomas Wieland, Jörg Heineke, Gergana...

NIMA-related kinase 9 regulates the phosphorylation of the essential myosin light chain in the heart.

DZHK authors: Marion Müller, Rose Eghbalian, Karen S. Frese, Jan Haas, Elham Kayvanpour, Farbod Sedaghat-Hamedani, Maximilian K. Lackner, Oguz F. Tugrul, Rewati Tappu, Diana...

Contractile Force of Transplanted Cardiomyocytes Actively Supports Heart Function After Injury

DZHK authors: Tim Stüdemann, Judith Rössinger, Christoph Manthey, Rajiven Srikantharajah, Constantin von Bibra, Aya Shibamiya, Maria Köhne, Thomas Eschenhagen, Florian Weinberger. ...

Smartphone-based screening for atrial fibrillation: a pragmatic randomized clinical trial. DZHK authors: Konstantinos Rizas, Lukas von Stülpnagel, Mathias Klemm, Steffen Massberg. Nature Medicine. DOI: 10.1038/s41591-022-01979-w

Origin and function of activated fibroblast states during zebrafish heart regeneration. DZHK authors: Bo Hu, Sara Lelek, Bastiaan Spanjaard, Hadil El-Sammak, Mariana Guedes Simões, Janita Mintcheva, Hananeh Aliee, Ronny Schäfer, Alexander M. Meyer, Fabian Theis, Didier Y. R....