DZHK Paper of the month

Mybpc3 Gene Therapy for Neonatal Cardiomyopathy Enables Long-Term Disease Prevention in Mice. (DZHK authors: Mearini, G., Stimpel, D., B., Weinberger, F., Kramer, E., Schlossarek, S., Braren, I., Katus, H. A., Muller, O. J., Eschenhagen, T. & Carrier, L.) Nature communications...

Cardiac myocyte-secreted cAMP exerts paracrine action via adenosine receptor activation, doi: 10.1172/JCI74349, (DZHK-Authors: Ahles, Dendorfer, Engelhardt)

Aspirin treatment and outcomes after percutaneous coronary intervention: results of the ISAR-ASPI registry, doi: 10.1016/j.jacc.2014.05.049, (DZHK-Autoren: Bernlochner, Schulz, Morath, Schunkert, Laugwitz, Kastrati, Sibbing)

Essential role of sympathetic endothelin A receptors for adverse cardiac remodeling, PNAS, doi: 10.1073/pnas.1409026111, (DZHK-Authors: Lehmann, Spiger, Wieland, Katus, Backs)

The Cardiac CaMKII Genes Delta and Gamma Contribute Redundantly to Adverse Remodeling but Inhibit Calcineurin-Induced Myocardial Hypertrophy, Circulation, doi:10.1161/CIRCULATIONAHA.114.006185 (DZHK authors: Lehmann, Hoting, Maier, Katus, Backs)

Silencing of CCR2 in myocarditis, European Heart Journal, doi:10.1093/eurheartj/ehu225 (DZHK-Autoren: Leuschner, Meder, Katus)

The beta-hydroxybutyrate receptor HCA2 activates a neuroprotective subset of macrophages, Nature Communications (2014), doi:10.1038/ncomms4944 (DZHK authors: Müller-Fielitz, Offermanns, Schwaninger)

Dichloroacetate prevents restenosis in preclinical animal models of vessel injury, Nature (2014), doi:10.1038/nature13232 (DZHK authors: Deuse, Zeller, Eschenhagen, Blankenberg, Reichenspurner, Schrepfer)

Assessment of microRNAs in patients with unstable angina pectoris, European Heart Journal, doi: 10.1093/eurheartj/ehu151, (DZHK-authors: Zeller, Keller, Wild, Münzel, Blankenberg)

MicroRNA-126-5p promotes endothelial proliferation and limits atherosclerosis by suppressing Dlk1, Nature Medicine 2014, doi:10.1038/nm.3487, (DZHK-authors: Schober, Weber)