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For the first time, engineered heart muscle (EHM) from human induced pluripotent stem cells (iPSCs) will be used to treat patients with heart failure. After regulatory approval, recruitment of the first patient for the first-in-class, first-in-patient BioVAT-HF-DZHK20 early...

Diastolic heart failure can be reliably detected with a newly developed magnetic resonance imaging (MRI) technology, shows a study by the German Centre for Cardiovascular Research (DZHK) at the Göttingen site. Until now, this was only possible with a heart catheterisation study,...

Circulatory disorders in the heart can have two causes: The large blood vessels can be narrowed, which can be treated with a stent, for example, or the small, finely branched vessels are no longer permeable. The latter is called impaired coronary microcirculation. A study by the...

What role does the so-called cytoskeleton play in heart failure? An international group of researchers led by Prof. Lucie Carrier from the University Medical Center Hamburg-Eppendorf (UKE) is now focusing on this area of heart disease, which has received little attention to date....

After an infection, the risk of a heart attack in cardiovascular risk patients increases up to twenty times. Scientists from the German Centre for Cardiovascular Research (DZHK) have found that the immune cells are involved in this in a mouse model. However, specific molecules...

People with high blood pressure get COVID-19 more severely and have an increased risk of death. Their immune cells are probably already pre-activated, but blood pressure-lowering ACE inhibitors could counteract the immune hyperactivation. This is reported by an interdisciplinary...

Conditions causing arrhythmia are among the most common cardiac conditions. A study headed by DZHK Scientist Prof. Georg Schmidt of the Technical University of Munich (TUM) has demonstrated for the first time that the nocturnal respiratory rate can help with an important...

To protect against sudden cardiac death, all patients with severe cardiac insufficiency, in which the heart's pumping capacity is highly restricted, are currently implanted with a defibrillator. But the procedure is risky and often unnecessary. Every year, the device triggers a...

DZHK researchers at Heidelberg University Hospital have developed a new method for "listening" to stressed heart muscle cells. They have been awarded the Wilhelm P. Winterstein Prize worth 10,000 euros for the technique of analysing proteins that myocardial cells release under...

A research study led by the University Hospital Frankfurt concludes that biomarkers indicate a critical course of COVID-19 disease in cardiovascular patients at an early stage. The findings could open up new treatment options, hoping DZHK scientist Dr. Sebastian Cremer, leading...